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β-actin mediated H3K27ac changes demonstrate the link between compartment switching and enhancer-dependent transcriptional regulation
BACKGROUND: Recent work has demonstrated that three-dimensional genome organization is directly affected by changes in the levels of nuclear cytoskeletal proteins such as β-actin. The mechanisms which translate changes in 3D genome structure into changes in transcription, however, are not fully unde...
Autores principales: | Mahmood, Syed Raza, Said, Nadine Hosny El, Gunsalus, Kristin C., Percipalle, Piergiorgio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875490/ https://www.ncbi.nlm.nih.gov/pubmed/36698204 http://dx.doi.org/10.1186/s13059-023-02853-9 |
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