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Notoginsenoside Fc ameliorates renal tubular injury and mitochondrial damage in acetaminophen-induced acute kidney injury partly by regulating SIRT3/SOD2 pathway

INTRODUCTION: Mitochondria dysfunction is one of the primary causes of tubular injury in acute kidney injury (AKI). Notoginsenoside Fc (Fc), a new saponin isolated from Panax notoginseng, exhibited numerous pharmacological actions. However, the beneficial effects of Fc on renal tubular impairment an...

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Detalles Bibliográficos
Autores principales: Wei, Miaomiao, Gao, Yuancheng, Cheng, Dongsheng, Zhang, Haiying, Zhang, Wei, Shen, Yilan, Huang, Qunwei, An, Xiaoning, Wang, Bing, Yu, Zhonghai, Wang, Niansong, Chen, Hongbo, Xu, Youhua, Gui, Dingkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875593/
https://www.ncbi.nlm.nih.gov/pubmed/36714147
http://dx.doi.org/10.3389/fmed.2022.1055252