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Notoginsenoside Fc ameliorates renal tubular injury and mitochondrial damage in acetaminophen-induced acute kidney injury partly by regulating SIRT3/SOD2 pathway
INTRODUCTION: Mitochondria dysfunction is one of the primary causes of tubular injury in acute kidney injury (AKI). Notoginsenoside Fc (Fc), a new saponin isolated from Panax notoginseng, exhibited numerous pharmacological actions. However, the beneficial effects of Fc on renal tubular impairment an...
Autores principales: | Wei, Miaomiao, Gao, Yuancheng, Cheng, Dongsheng, Zhang, Haiying, Zhang, Wei, Shen, Yilan, Huang, Qunwei, An, Xiaoning, Wang, Bing, Yu, Zhonghai, Wang, Niansong, Chen, Hongbo, Xu, Youhua, Gui, Dingkun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875593/ https://www.ncbi.nlm.nih.gov/pubmed/36714147 http://dx.doi.org/10.3389/fmed.2022.1055252 |
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