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Lipid‐Peptide‐mRNA Nanoparticles Augment Radioiodine Uptake in Anaplastic Thyroid Cancer

Restoring sodium iodide symporter (NIS) expression and function remains a major challenge for radioiodine therapy in anaplastic thyroid cancer (ATC). For more efficient delivery of messenger RNA (mRNA) to manipulate protein expression, a lipid‐peptide‐mRNA (LPm) nanoparticle (NP) is developed. The L...

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Detalles Bibliográficos
Autores principales: Li, Qinglin, Zhang, Lizhuo, Lang, Jiayan, Tan, Zhuo, Feng, Qingqing, Zhu, Fei, Liu, Guangna, Ying, Zhangguo, Yu, Xuefei, Feng, He, Yi, Heqing, Wen, Qingliang, Jin, Tiefeng, Cheng, Keman, Zhao, Xiao, Ge, Minghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875617/
https://www.ncbi.nlm.nih.gov/pubmed/36453580
http://dx.doi.org/10.1002/advs.202204334