Lipid Nanoparticle Delivery System for mRNA Encoding B7H3‐redirected Bispecific Antibody Displays Potent Antitumor Effects on Malignant Tumors

The therapeutic use of bispecific T‐cell engaging (BiTE) antibodies has shown great potential for treating malignancies. BiTE can simultaneously engage CD3ε on T cells and tumor antigen on cancer cells, thus exerting an effective antitumor effect. Nevertheless, challenges in production, manufacturin...

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Detalles Bibliográficos
Autores principales: Huang, Cheng, Duan, Xing, Wang, Jichao, Tian, Qingqing, Ren, Yangmei, Chen, Kepan, Zhang, Zongliang, Li, Yuanyou, Feng, Yunyu, Zhong, Kunhong, Wang, Yuelong, Zhou, Liangxue, Guo, Gang, Song, Xiangrong, Tong, Aiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875623/
https://www.ncbi.nlm.nih.gov/pubmed/36403209
http://dx.doi.org/10.1002/advs.202205532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875623/
https://www.ncbi.nlm.nih.gov/pubmed/36403209
http://dx.doi.org/10.1002/advs.202205532

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