Perylene‐Mediated Electron Leakage in Respiratory Chain to Trigger Endogenous ROS Burst for Hypoxic Cancer Chemo‐Immunotherapy

Perylene derivatives can be stimulated by the hypoxic tumor microenvironment to generate radical anion that is proposed to arouse electron exchange with oxidizing substance, and in turn, realize reactive oxygen species (ROS) burst. Here, three perylene therapeutic agents, PDI‐NI, PDIB‐NI, and PDIC‐N...

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Detalles Bibliográficos
Autores principales: Zhang, Bianbian, Zheng, Rijie, Liu, Yuting, Lou, Xue, Zhang, Wei, Cui, Zhanjun, Huang, Yongwei, Wang, Tie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875625/
https://www.ncbi.nlm.nih.gov/pubmed/36373677
http://dx.doi.org/10.1002/advs.202204498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875625/
https://www.ncbi.nlm.nih.gov/pubmed/36373677
http://dx.doi.org/10.1002/advs.202204498

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