Cargando…

Quantification of spatial pharmacogene expression heterogeneity in breast tumors

BACKGROUND: Chemotherapeutic drug concentrations vary across different regions of tumors and this is thought to be involved in development of chemotherapy resistance. Insufficient drug delivery to some regions of the tumor may be due to spatial differences in expression of genes involved in the disp...

Descripción completa

Detalles Bibliográficos
Autores principales: Powell, Nicholas R., Silvola, Rebecca M., Howard, John S., Badve, Sunil, Skaar, Todd C., Ipe, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875649/
https://www.ncbi.nlm.nih.gov/pubmed/35906899
http://dx.doi.org/10.1002/cnr2.1686