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Glutathione‐Responsive Nanoparticles of Camptothecin Prodrug for Cancer Therapy

Camptothecin (CPT) is a potent chemotherapeutic agent for various cancers, but the broader application of CPT is still hindered by its poor bioavailability and systemic toxicity. Here, a prodrug that releases CPT in response to glutathione (GSH), which is commonly overexpressed by cancer cells is re...

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Detalles Bibliográficos
Autores principales: Zhang, Lingpu, Zhu, Lin, Tang, Lin, Xie, Jiayi, Gao, Yajuan, Yu, Changyuan, Shang, Kun, Han, Hongbin, Liu, Chaoyong, Lu, Yunfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875659/
https://www.ncbi.nlm.nih.gov/pubmed/36442854
http://dx.doi.org/10.1002/advs.202205246