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Novel pentacyclic derivatives and benzylidenes of the progesterone series cause anti-estrogenic and antiproliferative effects and induce apoptosis in breast cancer cells

The promising antitumor effects of progesterone derivatives have been identified in many studies. However, the specific mechanism of action of this class of compounds has not been fully described. Therefore, in this study, we investigated the antiproliferative and (anti)estrogenic activities of nove...

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Detalles Bibliográficos
Autores principales: Scherbakov, Alexander M., Vorontsova, Svetlana K., Khamidullina, Alvina I, Mrdjanovic, Jasminka, Andreeva, Olga E., Bogdanov, Fedor B., Salnikova, Diana I., Jurisic, Vladimir, Zavarzin, Igor V., Shirinian, Valerii Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9875769/
https://www.ncbi.nlm.nih.gov/pubmed/36695998
http://dx.doi.org/10.1007/s10637-023-01332-z