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Leveraging an advanced simulated moving bed approach to achieve 3-component separation for enhanced impurity removal in a non-affinity cation exchange capture step

One of the key challenges in downstream bioprocessing is to obtain products of high purity in a productive fashion through the effective removal of process and product related impurities. While a classical simulated moving bed (SMB) system operation can typically achieve a 2-component separation bet...

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Detalles Bibliográficos
Autores principales: Chen, Serene W., Zheng, Zi Ying, Mahfut, Farouq Bin, Yang, Yuansheng, Ogino, Masahiro, Okada, Kazuo, Sato, Kohei, Zhang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876269/
https://www.ncbi.nlm.nih.gov/pubmed/36696419
http://dx.doi.org/10.1371/journal.pone.0280760