Genome concentration, characterization, and integrity analysis of recombinant adeno-associated viral vectors using droplet digital PCR

Precise, reproducible characterization of AAV is critical for comparing preclinical results between laboratories and determining a safe and effective clinical dose for gene therapy applications. In this study, we systematically evaluated numerous parameters to produce a simple and robust ddPCR proto...

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Detalles Bibliográficos
Autores principales: Prantner, Andrew, Maar, Dianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876284/
https://www.ncbi.nlm.nih.gov/pubmed/36696399
http://dx.doi.org/10.1371/journal.pone.0280242

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876284/
https://www.ncbi.nlm.nih.gov/pubmed/36696399
http://dx.doi.org/10.1371/journal.pone.0280242

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