Cargando…
Genome concentration, characterization, and integrity analysis of recombinant adeno-associated viral vectors using droplet digital PCR
Precise, reproducible characterization of AAV is critical for comparing preclinical results between laboratories and determining a safe and effective clinical dose for gene therapy applications. In this study, we systematically evaluated numerous parameters to produce a simple and robust ddPCR proto...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876284/ https://www.ncbi.nlm.nih.gov/pubmed/36696399 http://dx.doi.org/10.1371/journal.pone.0280242 |