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Growth and adaptation mechanisms of tumour spheroids with time-dependent oxygen availability

Tumours are subject to external environmental variability. However, in vitro tumour spheroid experiments, used to understand cancer progression and develop cancer therapies, have been routinely performed for the past fifty years in constant external environments. Furthermore, spheroids are typically...

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Detalles Bibliográficos
Autores principales: Murphy, Ryan J., Gunasingh, Gency, Haass, Nikolas K., Simpson, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876349/
https://www.ncbi.nlm.nih.gov/pubmed/36634128
http://dx.doi.org/10.1371/journal.pcbi.1010833