Cargando…
The Q163C/Q309C mutant of α(M)I-domain is an active variant suitable for NMR characterization
Integrin α(M)β(2) (Mac-1, CD11b/CD18, CR3) is an important adhesion receptor expressed on monocytes. Mac-1 is responsible for mediating cell migration, phagocytosis, degranulation as well as cell-cell fusion. It is also the most promiscuous integrin in terms of ligand specificity with over 100 ligan...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876370/ https://www.ncbi.nlm.nih.gov/pubmed/36696377 http://dx.doi.org/10.1371/journal.pone.0280778 |