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Identification of gluten T cell epitopes driving celiac disease

CD4(+) T cells specific for cereal gluten proteins are key players in celiac disease (CeD) pathogenesis. While several CeD-relevant gluten T cell epitopes have been identified, epitopes recognized by a substantial proportion of gluten-reactive T cells remain unknown. The identification of such CeD-d...

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Detalles Bibliográficos
Autores principales: Chlubnová, Markéta, Christophersen, Asbjørn O., Sandve, Geir Kjetil F., Lundin, Knut E.A, Jahnsen, Jørgen, Dahal-Koirala, Shiva, Sollid, Ludvig M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876541/
https://www.ncbi.nlm.nih.gov/pubmed/36696493
http://dx.doi.org/10.1126/sciadv.ade5800