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Mechanoregulatory role of TRPV4 in prenatal skeletal development

Biophysical cues are essential for guiding skeletal development, but the mechanisms underlying the mechanical regulation of cartilage and bone formation are unknown. TRPV4 is a mechanically sensitive ion channel involved in cartilage and bone cell mechanosensing, mutations of which lead to skeletal...

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Detalles Bibliográficos
Autores principales: Khatib, Nidal S., Monsen, James, Ahmed, Saima, Huang, Yuming, Hoey, David A., Nowlan, Niamh C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876556/
https://www.ncbi.nlm.nih.gov/pubmed/36696489
http://dx.doi.org/10.1126/sciadv.ade2155