Increased expression of GPX4 promotes the tumorigenesis of thyroid cancer by inhibiting ferroptosis and predicts poor clinical outcomes

Background: Ferroptosis plays a critical role in suppressing cancer progression, and its essential regulator is glutathione peroxidase 4 (GPX4). High GPX4 expression can inhibit accumulation of iron, thus suppressing ferroptosis. However, its function in thyroid cancer has not been fully illuminated...

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Detalles Bibliográficos
Autores principales: Chen, Huanjie, Peng, Fang, Xu, Jingchao, Wang, Guangzhi, Zhao, Yongfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876627/
https://www.ncbi.nlm.nih.gov/pubmed/36626251
http://dx.doi.org/10.18632/aging.204473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876627/
https://www.ncbi.nlm.nih.gov/pubmed/36626251
http://dx.doi.org/10.18632/aging.204473

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