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Genetic deficiency and pharmacological modulation of RORα regulate laser-induced choroidal neovascularization

Choroidal neovascularization (CNV) causes acute vision loss in neovascular age-related macular degeneration (AMD). Genetic variations of the nuclear receptor RAR-related orphan receptor alpha (RORα) have been linked with neovascular AMD, yet its specific role in pathological CNV development is not e...

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Detalles Bibliográficos
Autores principales: Liu, Chi-Hsiu, Yemanyi, Felix, Bora, Kiran, Kushwah, Neetu, Blomfield, Alexandra K., Kamenecka, Theodore M., SanGiovanni, John Paul, Sun, Ye, Solt, Laura A., Chen, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876633/
https://www.ncbi.nlm.nih.gov/pubmed/36626253
http://dx.doi.org/10.18632/aging.204480