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Genetic deficiency and pharmacological modulation of RORα regulate laser-induced choroidal neovascularization
Choroidal neovascularization (CNV) causes acute vision loss in neovascular age-related macular degeneration (AMD). Genetic variations of the nuclear receptor RAR-related orphan receptor alpha (RORα) have been linked with neovascular AMD, yet its specific role in pathological CNV development is not e...
Autores principales: | Liu, Chi-Hsiu, Yemanyi, Felix, Bora, Kiran, Kushwah, Neetu, Blomfield, Alexandra K., Kamenecka, Theodore M., SanGiovanni, John Paul, Sun, Ye, Solt, Laura A., Chen, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876633/ https://www.ncbi.nlm.nih.gov/pubmed/36626253 http://dx.doi.org/10.18632/aging.204480 |
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