A deep tabular data learning model predicting cisplatin sensitivity identifies BCL2L1 dependency in cancer

Cisplatin, a platinum-based chemotherapeutic agent, is widely used as a front-line treatment for several malignancies. However, treatment outcomes vary widely due to intrinsic and acquired resistance. In this study, cisplatin-perturbed gene expression and pathway enrichment were used to define a gen...

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Detalles Bibliográficos
Autores principales: Nasimian, Ahmad, Ahmed, Mehreen, Hedenfalk, Ingrid, Kazi, Julhash U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876747/
https://www.ncbi.nlm.nih.gov/pubmed/36733702
http://dx.doi.org/10.1016/j.csbj.2023.01.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876747/
https://www.ncbi.nlm.nih.gov/pubmed/36733702
http://dx.doi.org/10.1016/j.csbj.2023.01.020

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