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A deep tabular data learning model predicting cisplatin sensitivity identifies BCL2L1 dependency in cancer
Cisplatin, a platinum-based chemotherapeutic agent, is widely used as a front-line treatment for several malignancies. However, treatment outcomes vary widely due to intrinsic and acquired resistance. In this study, cisplatin-perturbed gene expression and pathway enrichment were used to define a gen...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876747/ https://www.ncbi.nlm.nih.gov/pubmed/36733702 http://dx.doi.org/10.1016/j.csbj.2023.01.020 |