DeepCubist: Molecular Generator for Designing Peptidomimetics based on Complex three-dimensional scaffolds

Mimicking bioactive conformations of peptide segments involved in the formation of protein-protein interfaces with small molecules is thought to represent a promising strategy for the design of protein-protein interaction (PPI) inhibitors. For compound design, the use of three-dimensional (3D) scaff...

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Detalles Bibliográficos
Autores principales: Umedera, Kohei, Yoshimori, Atsushi, Chen, Hengwei, Kouji, Hiroyuki, Nakamura, Hiroyuki, Bajorath, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876871/
https://www.ncbi.nlm.nih.gov/pubmed/36462089
http://dx.doi.org/10.1007/s10822-022-00493-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876871/
https://www.ncbi.nlm.nih.gov/pubmed/36462089
http://dx.doi.org/10.1007/s10822-022-00493-y

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