Pacritinib inhibits glucose consumption in squamous cell lung cancer cells by targeting FLT3

Squamous cell lung cancer maintains its growth through elevated glucose consumption, but selective glucose consumption inhibitors are lacking. Here, we discovered using a high-throughput screen new compounds that block glucose consumption in three squamous cell lung cancer cell lines and identified...

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Detalles Bibliográficos
Autores principales: Ghezzi, Chiara, Chen, Bao Ying, Damoiseaux, Robert, Clark, Peter M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876922/
https://www.ncbi.nlm.nih.gov/pubmed/36697489
http://dx.doi.org/10.1038/s41598-023-28576-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876922/
https://www.ncbi.nlm.nih.gov/pubmed/36697489
http://dx.doi.org/10.1038/s41598-023-28576-2

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