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Pacritinib inhibits glucose consumption in squamous cell lung cancer cells by targeting FLT3
Squamous cell lung cancer maintains its growth through elevated glucose consumption, but selective glucose consumption inhibitors are lacking. Here, we discovered using a high-throughput screen new compounds that block glucose consumption in three squamous cell lung cancer cell lines and identified...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876922/ https://www.ncbi.nlm.nih.gov/pubmed/36697489 http://dx.doi.org/10.1038/s41598-023-28576-2 |