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Quantification of localized NAD(+) changes reveals unique specificity of NAD(+) regulation in the hypothalamus

Recently, it has become a consensus that systemic decreases in NAD(+) are a critical trigger for age-associated functional decline in multiple tissues and organs. The hypothalamus, which contains several functionally distinct subregions called nuclei, functions as a high-order control center of agin...

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Detalles Bibliográficos
Autores principales: Johnson, Sean, Yoshioka, Kiyoshi, Brace, Cynthia S., Imai, Shin-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876928/
https://www.ncbi.nlm.nih.gov/pubmed/36697402
http://dx.doi.org/10.1038/s41514-023-00098-1