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Quantification of localized NAD(+) changes reveals unique specificity of NAD(+) regulation in the hypothalamus
Recently, it has become a consensus that systemic decreases in NAD(+) are a critical trigger for age-associated functional decline in multiple tissues and organs. The hypothalamus, which contains several functionally distinct subregions called nuclei, functions as a high-order control center of agin...
Autores principales: | Johnson, Sean, Yoshioka, Kiyoshi, Brace, Cynthia S., Imai, Shin-ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876928/ https://www.ncbi.nlm.nih.gov/pubmed/36697402 http://dx.doi.org/10.1038/s41514-023-00098-1 |
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