Accuracy of haplotype estimation and whole genome imputation affects complex trait analyses in complex biobanks

Sample recruitment for research consortia, biobanks, and personal genomics companies span years, necessitating genotyping in batches, using different technologies. As marker content on genotyping arrays varies, integrating such datasets is non-trivial and its impact on haplotype estimation (phasing)...

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Detalles Bibliográficos
Autores principales: Appadurai, Vivek, Bybjerg-Grauholm, Jonas, Krebs, Morten Dybdahl, Rosengren, Anders, Buil, Alfonso, Ingason, Andrés, Mors, Ole, Børglum, Anders D., Hougaard, David M., Nordentoft, Merete, Mortensen, Preben B., Delaneau, Olivier, Werge, Thomas, Schork, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876938/
https://www.ncbi.nlm.nih.gov/pubmed/36697501
http://dx.doi.org/10.1038/s42003-023-04477-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9876938/
https://www.ncbi.nlm.nih.gov/pubmed/36697501
http://dx.doi.org/10.1038/s42003-023-04477-y

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