CPEB1-dependent disruption of the mRNA translation program in oocytes during maternal aging

The molecular causes of deteriorating oocyte quality during aging are poorly defined. Since oocyte developmental competence relies on post-transcriptional regulations, we tested whether defective mRNA translation contributes to this decline in quality. Disruption in ribosome loading on maternal tran...

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Detalles Bibliográficos
Autores principales: Takahashi, Nozomi, Franciosi, Federica, Daldello, Enrico Maria, Luong, Xuan G., Althoff, Peter, Wang, Xiaotian, Conti, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877008/
https://www.ncbi.nlm.nih.gov/pubmed/36697412
http://dx.doi.org/10.1038/s41467-023-35994-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877008/
https://www.ncbi.nlm.nih.gov/pubmed/36697412
http://dx.doi.org/10.1038/s41467-023-35994-3

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