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Cyperotundone combined with adriamycin induces apoptosis in MCF-7 and MCF-7/ADR cancer cells by ROS generation and NRF2/ARE signaling pathway

Breast cancer has become the most prevalent cancer, globally. Adriamycin is a first-line chemotherapeutic agent, however, cancer cells acquire resistance to it, which is one of the most common causes of treatment failure. ROS and NRF2 are essential oxidative stress factors that play a key role in th...

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Detalles Bibliográficos
Autores principales: Shao, Wenna, Wang, Xinzhao, Liu, Zhaoyun, Song, Xiang, Wang, Fukai, Liu, Xiaoyu, Yu, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877033/
https://www.ncbi.nlm.nih.gov/pubmed/36697441
http://dx.doi.org/10.1038/s41598-022-26767-x