A FRET-based respirasome assembly screen identifies spleen tyrosine kinase as a target to improve muscle mitochondrial respiration and exercise performance in mice

Aerobic muscle activities predominantly depend on fuel energy supply by mitochondrial respiration, thus, mitochondrial activity enhancement may become a therapeutic intervention for muscle disturbances. The assembly of mitochondrial respiratory complexes into higher-order “supercomplex” structures h...

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Detalles Bibliográficos
Autores principales: Kobayashi, Ami, Azuma, Kotaro, Takeiwa, Toshihiko, Kitami, Toshimori, Horie, Kuniko, Ikeda, Kazuhiro, Inoue, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877034/
https://www.ncbi.nlm.nih.gov/pubmed/36697396
http://dx.doi.org/10.1038/s41467-023-35865-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877034/
https://www.ncbi.nlm.nih.gov/pubmed/36697396
http://dx.doi.org/10.1038/s41467-023-35865-x

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