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Pathogenic Mechanisms of Pulmonary Arterial Hypertension: Homeostasis Imbalance of Endothelium-Derived Relaxing and Contracting Factors

Pulmonary arterial hypertension (PAH) is a progressive and fatal disease. Sustained pulmonary vasoconstriction and concentric pulmonary vascular remodeling contribute to the elevated pulmonary vascular resistance and pulmonary artery pressure in PAH. Endothelial cells regulate vascular tension by pr...

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Detalles Bibliográficos
Autores principales: Zhu, Jinsheng, Yang, Lei, Jia, Yangfan, Balistrieri, Angela, Fraidenburg, Dustin R., Wang, Jian, Tang, Haiyang, Yuan, Jason X-J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877237/
https://www.ncbi.nlm.nih.gov/pubmed/36713766
http://dx.doi.org/10.1016/j.jacasi.2022.09.010