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Pathogenic Mechanisms of Pulmonary Arterial Hypertension: Homeostasis Imbalance of Endothelium-Derived Relaxing and Contracting Factors
Pulmonary arterial hypertension (PAH) is a progressive and fatal disease. Sustained pulmonary vasoconstriction and concentric pulmonary vascular remodeling contribute to the elevated pulmonary vascular resistance and pulmonary artery pressure in PAH. Endothelial cells regulate vascular tension by pr...
Autores principales: | Zhu, Jinsheng, Yang, Lei, Jia, Yangfan, Balistrieri, Angela, Fraidenburg, Dustin R., Wang, Jian, Tang, Haiyang, Yuan, Jason X-J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877237/ https://www.ncbi.nlm.nih.gov/pubmed/36713766 http://dx.doi.org/10.1016/j.jacasi.2022.09.010 |
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