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Innate immunity mediator STING modulates nascent DNA metabolism at stalled forks in human cells
Background: The cGAS/STING pathway, part of the innate immune response to foreign DNA, can be activated by cell’s own DNA arising from the processing of the genome, including the degradation of nascent DNA at arrested replication forks, which can be upregulated in cancer cells. Recent evidence raise...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877313/ https://www.ncbi.nlm.nih.gov/pubmed/36710880 http://dx.doi.org/10.3389/fmolb.2022.1048726 |