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A comparative study of COVID-19 transcriptional signatures between clinical samples and preclinical cell models in the search for disease master regulators and drug repositioning candidates

Coronavirus disease 2019 (COVID-19) is an acute viral disease with millions of cases worldwide. Although the number of daily new cases and deaths has been dropping, there is still a need for therapeutic alternatives to deal with severe cases. A promising strategy to prospect new therapeutic candidat...

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Detalles Bibliográficos
Autores principales: Chapola, Henrique, de Bastiani, Marco Antônio, Duarte, Marcelo Mendes, Freitas, Matheus Becker, Schuster, Jussara Severo, de Vargas, Daiani Machado, Klamt, Fábio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877318/
https://www.ncbi.nlm.nih.gov/pubmed/36709793
http://dx.doi.org/10.1016/j.virusres.2023.199053