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A comparative study of COVID-19 transcriptional signatures between clinical samples and preclinical cell models in the search for disease master regulators and drug repositioning candidates
Coronavirus disease 2019 (COVID-19) is an acute viral disease with millions of cases worldwide. Although the number of daily new cases and deaths has been dropping, there is still a need for therapeutic alternatives to deal with severe cases. A promising strategy to prospect new therapeutic candidat...
Autores principales: | Chapola, Henrique, de Bastiani, Marco Antônio, Duarte, Marcelo Mendes, Freitas, Matheus Becker, Schuster, Jussara Severo, de Vargas, Daiani Machado, Klamt, Fábio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877318/ https://www.ncbi.nlm.nih.gov/pubmed/36709793 http://dx.doi.org/10.1016/j.virusres.2023.199053 |
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