Transcription factor Ap2b regulates the mouse autosomal recessive polycystic kidney disease genes, Pkhd1 and Cys1

Transcription factor Ap2b (TFAP2B), an AP-2 family transcription factor, binds to the palindromic consensus DNA sequence, 5′-GCCN(3-5)GGC-3’. Mice lacking functional Tfap2b gene die in the perinatal or neonatal period with cystic dilatation of the kidney distal tubules and collecting ducts, a phenot...

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Detalles Bibliográficos
Autores principales: Wu, Maoqing, Harafuji, Naoe, O’Connor, Amber K., Caldovic, Ljubica, Guay-Woodford, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877354/
https://www.ncbi.nlm.nih.gov/pubmed/36710876
http://dx.doi.org/10.3389/fmolb.2022.946344

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877354/
https://www.ncbi.nlm.nih.gov/pubmed/36710876
http://dx.doi.org/10.3389/fmolb.2022.946344

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