Omicron‐specific mRNA vaccine induced cross‐protective immunity against ancestral SARS‐CoV‐2 infection with low neutralizing antibodies

The major challenge in COVID‐19 vaccine effectiveness is immune escape by SARS‐CoV‐2 variants. To overcome this, an Omicron‐specific messenger RNA (mRNA) vaccine was designed. The extracellular domain of the spike of the Omicron variant was fused with a modified GCN4 trimerization domain with low im...

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Detalles Bibliográficos
Autores principales: Shen, Kuan‐Yin, Yang, Chung‐Hsiang, Chen, Chiung‐Tong, Ho, Hui‐Min, Chiu, Fang‐Feng, Huang, Chiung‐Yi, Liao, Hung‐Chun, Hsu, Chia‐Wei, Yu, Guann‐Yi, Liao, Ching‐Len, Chen, Hsin‐Wei, Huang, Ming‐Hsi, Liu, Shih‐Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Short Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877661/
https://www.ncbi.nlm.nih.gov/pubmed/36458553
http://dx.doi.org/10.1002/jmv.28370

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9877661/
https://www.ncbi.nlm.nih.gov/pubmed/36458553
http://dx.doi.org/10.1002/jmv.28370

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