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RIG-I and MDA5 are modulated by bone morphogenetic protein (BMP6) and are essential for restricting Zika virus infection in human Sertoli cells

Sexual transmission of Zika virus (ZIKV) is associated with virus persistence in the testes and shedding in the seminal fluid for months after recovery. We previously demonstrated that ZIKV can establish long-term replication without causing cytotoxicity in human Sertoli cells (SC), responsible for...

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Detalles Bibliográficos
Autores principales: Jiyarom, Boonyanudh, Giannakopoulos, Stefanos, Strange, Daniel P., Panova, Nataliya, Gale, Michael, Verma, Saguna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878278/
https://www.ncbi.nlm.nih.gov/pubmed/36713156
http://dx.doi.org/10.3389/fmicb.2022.1062499