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Oxymatrine ameliorates experimental autoimmune encephalomyelitis by rebalancing the homeostasis of gut microbiota and reducing blood-brain barrier disruption

BACKGROUND: Increasing evidence suggests that gut dysbiosis can directly or indirectly affect the immune system through the brain-gut axis and play a role in the occurrence and development of Multiple sclerosis (MS). Oxymatrine (OMAT) has been shown to ameliorate the symptoms of MS in the classical...

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Detalles Bibliográficos
Autores principales: Zhang, Ming-Liang, Li, Wei-Xia, Wang, Xiao-Yan, Wu, Ya-Li, Chen, Xiao-Fei, Zhang, Hui, Yang, Liu-Qing, Wu, Cheng-Zhao, Zhang, Shu-Qi, Chen, Yu-Long, Feng, Ke-Ran, Wang, Bin, Niu, Lu, Kong, De-Xin, Tang, Jin-Fa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878311/
https://www.ncbi.nlm.nih.gov/pubmed/36710971
http://dx.doi.org/10.3389/fcimb.2022.1095053