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Regulators, functions, and mechanotransduction pathways of matrix stiffness in hepatic disease

The extracellular matrix (ECM) provides physical support and imparts significant biochemical and mechanical cues to cells. Matrix stiffening is a hallmark of liver fibrosis and is associated with many hepatic diseases, especially liver cirrhosis and carcinoma. Increased matrix stiffness is not only...

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Detalles Bibliográficos
Autores principales: Guo, Ting, Wantono, Cindy, Tan, Yuyong, Deng, Feihong, Duan, Tianying, Liu, Deliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878334/
https://www.ncbi.nlm.nih.gov/pubmed/36711017
http://dx.doi.org/10.3389/fphys.2023.1098129