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The HDAC inhibitor zabadinostat is a systemic regulator of adaptive immunity

Protein acetylation plays a key role in regulating cellular processes and is subject to aberrant control in diverse pathologies. Although histone deacetylase (HDAC) inhibitors are approved drugs for certain cancers, it is not known whether they can be deployed in other therapeutic contexts. We have...

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Detalles Bibliográficos
Autores principales: Liu, Geng, Barczak, Wojciech, Lee, Lian Ni, Shrestha, Amit, Provine, Nicholas M., Albayrak, Gulsah, Zhu, Hong, Hutchings, Claire, Klenerman, Paul, La Thangue, Nicholas B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878486/
https://www.ncbi.nlm.nih.gov/pubmed/36702861
http://dx.doi.org/10.1038/s42003-023-04485-y