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The HDAC inhibitor zabadinostat is a systemic regulator of adaptive immunity
Protein acetylation plays a key role in regulating cellular processes and is subject to aberrant control in diverse pathologies. Although histone deacetylase (HDAC) inhibitors are approved drugs for certain cancers, it is not known whether they can be deployed in other therapeutic contexts. We have...
Autores principales: | Liu, Geng, Barczak, Wojciech, Lee, Lian Ni, Shrestha, Amit, Provine, Nicholas M., Albayrak, Gulsah, Zhu, Hong, Hutchings, Claire, Klenerman, Paul, La Thangue, Nicholas B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878486/ https://www.ncbi.nlm.nih.gov/pubmed/36702861 http://dx.doi.org/10.1038/s42003-023-04485-y |
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