Improved Process for the Preparation of Naloxegol Oxalate, an Opiod Receptor Antagonist

[Image: see text] The present article discloses an improved and robust commercial process of the modern medicine naloxegol oxalate, which is used to treat opioid-induced constipation. The synthesis originates from the easily available key starting material, viz., naloxone, and ends with the oxalate...

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Detalles Bibliográficos
Autores principales: Velugula, Siva Rama Kasibabu, Misra, Nimesh Chandra, Chapala, Suresh, Aaramadaka, Sunil Kumar Reddy, Chavakula, Ramadas, Sanasi, Paul Douglas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878627/
https://www.ncbi.nlm.nih.gov/pubmed/36713715
http://dx.doi.org/10.1021/acsomega.2c07305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878627/
https://www.ncbi.nlm.nih.gov/pubmed/36713715
http://dx.doi.org/10.1021/acsomega.2c07305

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