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Improved Process for the Preparation of Naloxegol Oxalate, an Opiod Receptor Antagonist
[Image: see text] The present article discloses an improved and robust commercial process of the modern medicine naloxegol oxalate, which is used to treat opioid-induced constipation. The synthesis originates from the easily available key starting material, viz., naloxone, and ends with the oxalate...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878627/ https://www.ncbi.nlm.nih.gov/pubmed/36713715 http://dx.doi.org/10.1021/acsomega.2c07305 |