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Placental macrophages present distinct polarization pattern and effector functions depending on clinical onset of preeclampsia

Hofbauer cells (HBCs) are resident macrophages of the human placenta, regulating immune tolerance and tissue homeostasis. HBCs of a normal placenta (CTR) exhibit mainly an anti-inflammatory M2 phenotype. Under exaggerated chronic inflammation during pregnancy, as in preeclampsia (PE), a phenotypic s...

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Detalles Bibliográficos
Autores principales: Mercnik, Monika Horvat, Schliefsteiner, Carolin, Fluhr, Herbert, Wadsack, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878680/
https://www.ncbi.nlm.nih.gov/pubmed/36713449
http://dx.doi.org/10.3389/fimmu.2022.1095879