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Placental macrophages present distinct polarization pattern and effector functions depending on clinical onset of preeclampsia
Hofbauer cells (HBCs) are resident macrophages of the human placenta, regulating immune tolerance and tissue homeostasis. HBCs of a normal placenta (CTR) exhibit mainly an anti-inflammatory M2 phenotype. Under exaggerated chronic inflammation during pregnancy, as in preeclampsia (PE), a phenotypic s...
Autores principales: | Mercnik, Monika Horvat, Schliefsteiner, Carolin, Fluhr, Herbert, Wadsack, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878680/ https://www.ncbi.nlm.nih.gov/pubmed/36713449 http://dx.doi.org/10.3389/fimmu.2022.1095879 |
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