Acidification-Induced Structure Evolution of Lipid Nanoparticles Correlates with Their In Vitro Gene Transfections

[Image: see text] The rational design of lipid nanoparticles (LNPs) for enhanced gene delivery remains challenging because of incomplete knowledge of their formulation–structure relationship that impacts their intracellular behavior and consequent function. Small-angle neutron scattering has been us...

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Detalles Bibliográficos
Autores principales: Li, Zongyi, Carter, Jessica, Santos, Luis, Webster, Carl, van der Walle, Christopher F., Li, Peixun, Rogers, Sarah E., Lu, Jian Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878718/
https://www.ncbi.nlm.nih.gov/pubmed/36608273
http://dx.doi.org/10.1021/acsnano.2c06213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878718/
https://www.ncbi.nlm.nih.gov/pubmed/36608273
http://dx.doi.org/10.1021/acsnano.2c06213

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