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PCDH17 gene promoter methylation status in a cohort of Egyptian women with epithelial ovarian cancer

BACKGROUND AND OBJECTIVE: Ovarian cancer is a leading cause of female mortality. Epigenetic changes occur in early stages of carcinogenesis and represent a marker for cancer diagnosis. Protocadherin 17 (PCDH17) is a tumor suppressor gene involved in cell adhesion and apoptosis. The methylation of PC...

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Detalles Bibliográficos
Autores principales: Elsharkawi, Sherif Mohamed, Elkaffash, Dalal, Moez, Pacint, El-Etreby, Nour, Sheta, Eman, Taleb, Raghda Saad Zaghloul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878799/
https://www.ncbi.nlm.nih.gov/pubmed/36698136
http://dx.doi.org/10.1186/s12885-023-10549-3