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Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity

Cadherin EGF LAG seven-pass G-type receptor (Celsr) proteins 1-3 comprise a subgroup of adhesion GPCRs whose functions range from planar cell polarity (PCP) signaling to axon pathfinding and ciliogenesis. Like its Drosophila ortholog, Flamingo, mammalian Celsr1 is a core component of the PCP pathway...

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Detalles Bibliográficos
Autores principales: Basta, Lena P., Sil, Parijat, Jones, Rebecca A., Little, Katherine A., Hayward-Lara, Gabriela, Devenport, Danelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878842/
https://www.ncbi.nlm.nih.gov/pubmed/36712970
http://dx.doi.org/10.3389/fcell.2022.1064907