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Aβ42 treatment of the brain side reduced the level of flotillin from endothelial cells on the blood side via FGF-2 signaling in a blood–brain barrier model

Our previous study showed that the flotillin level is decreased in the blood of patients with Alzheimer’s disease (AD) when compared to that of patients with non-AD and vascular dementia; however, the molecular mechanism remains to be determined. In this study, to elucidate whether Aβ accumulation i...

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Detalles Bibliográficos
Autores principales: Nakamura, Tomohisa, Hashita, Tadahiro, Chen, Yuxin, Gao, Yuan, Sun, Yang, Islam, Sadequl, Sato, Hiroyuki, Shibuya, Yasuyuki, Zou, Kun, Matsunaga, Tamihide, Michikawa, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9878866/
https://www.ncbi.nlm.nih.gov/pubmed/36698209
http://dx.doi.org/10.1186/s13041-023-01005-1